When His relatives [or friends] heard about this [i.e., all that He was doing], they went out to take custody of Him [for safety reasons (?)], for people were saying, “He has lost his mind.”
Then Jesus’ [half-] brothers said to Him, “You should leave here and go to Judea so your disciples [there] can see the [supernatural] deeds you are performing.
While Jesus was still speaking to the large crowds, His mother and [half-] brothers were standing outside [of the large house. See 13:1] wanting to speak to Him.