But they [i.e., the world] will do all these things to you for my name’s sake [i.e., because you are my disciples], for they do not know Him [i.e., God], who sent me.
who killed the Lord Jesus and the [Old Testament] prophets and also drove us [apostles] out [of Thessalonica and Berea. See Acts 17]. They are not pleasing to God and are hostile to all people,
The Pharisees [i.e., a strict sect of the Jewish religion] heard the crowd whispering these things about Him, so the leading priests and Pharisees sent some Temple guards to arrest Him.
Then Simeon [asked God to] bless them and said to Jesus’ mother Mary, “Look, many Israelites will be caused to fall [i.e., into spiritual ruin] or rise [i.e., to spiritual renewal] because of Him. And [He will be] a ‘sign’ [for people] to speak against,
The Jews [i.e., the authorities] replied, “Now we know that you are dominated by an evil spirit. Abraham and the prophets [all] died and [yet] you are saying, ‘If a person obeys my message, he will never experience death.’
[Along the way] they strengthened the hearts of the disciples, urging them to continue [to believe and practice] the faith and [explaining] that entering God's [heavenly] kingdom [See II Tim. 4:18] requires enduring many trials.
And they said to Him, “[Yes], we are able to.” And Jesus said to them, “The cup [of suffering] that I [will] drink, you [also] will drink. And the immersion [with agony] with which I am [to be] immersed, you [also] will be immersed.